Reader Remarks on:

Cephalosporins in Patients with Penicillin Allergy: Use Them . . . but Be Careful

cross sensitivity
role of montleukast in stevens-johonson reaction
cephalosporin and pcn reactions

cross sensitivity

R H Schneider, 28 May 2009 12:58 PM EST

Competing interests: None declared

Have used cephalosporins in pts "said" to have pen allergy. No observed reaction in >40 yrs. Luck? Reactions rarer than stated. Dx of pen allergy incorrect? Other reason(s)?

role of montleukast in stevens-johonson reaction

Maged A. Zaki, Student's Hospital, HIO, Alexandria ,Egypt, 8 Jun 2009 1:12 PM EST

Competing interests: None declared

In 2 cases of stevens- johnson reaction due to phenitoin in pediatric age , I used montleukastin (antileukotrien) in addition to other standard treatments, the result was more than satisfactory, I think this group of medications, needs to be further studied in such cases as a standard additional line of treatment

cephalosporin and pcn reactions

A. Pennisson,MD, 9 Jun 2009 12:33 PM EST

Competing interests: None declared

Same here - no reactions in 20 years with cephalosporins in those with pcn reactions. I do not use in those with hx of anaphylaxis unless necessary and must skin test and desensitive first.

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