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Reader Remarks on:

Preventing Rheumatic Fever: A New Guideline from the AHA

Culture for GAS

HAI PHUOC LE, EDMONTON,ALBERTA,CANADA, 3 Apr 2009 1:05 PM EST

Competing interests: None declared

If pretest probability is high, why should culture ( or rapid antigen test ) be performed /

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adults and amoxicilline

jasna mv, 14 Apr 2009 10:53 AM EST

Competing interests: None declared

so 1gr once a day if they have more then 20kg even if they have 100kg? is that correct?

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Timing

werner kaiser, practician, 14 Apr 2009 10:53 AM EST

Competing interests: None declared

after taken culture start with antibiotic therapy instantly?

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Response to queries

Howard Bauchner, BUSM and Associate Editor, Journal Watch Pediatrics and Adolescent Medicine, 17 Apr 2009 1:56 AM EST

Competing interests: None declared

1. Guidelines still suggest a positive rapid strept or culture - even if high pretest probability; would never excede 50-75% confirmation. 2. According to guideline - Table 2 - maximum dose is 1 gram. 3. Can culture and treat - although data about relief of symptoms with antibiotics is minimal.

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